生物安全程序

  1. 部门目录
  2. 生物安全程序
科学实验室里的人
我们做什么

The purpose of this site is to provide guidance and resources to ensure any 研究 involving recombinant DNA or biological material is conducted in a manner that protects the health of 研究ers, RIC社区, 还有环境.

联系信息
程序的椅子

黛博拉·布里特

We appreciate efforts to streamline project registration procedures and welcome any suggestions from principal investigators and the broader community

请注意

Some of the guidance requires active participation of principal investigators to comply and adhere to the policies of RIC, 疾病控制中心, 美国国立卫生研究院, 国家科学基金会, 以及职业安全与健康管理局.

计划的细节

你们的合规性对RIC生物安全计划目标的成功至关重要. Those working with recombinant DNA (rDNA) and/or biological materials are required to submit a 生物项目登记表 to the 院校生物安全委员会. 在某些情况下，在实验室工作开始之前，表格必须经过审查. 以下活动免予全面审查, 但仍需提交生物项目登记表.

对健康或环境不构成重大风险的rDNA

不在生物体或病毒中的rDNA

完全由单个非染色体或病毒DNA来源的DNA片段组成的rDNA

rDNA consisting entirely of DNA from a prokaryotic host including its indigenous plasmids or viruses when propagated only in that host or when transferred to another host by well established physiological means.

完全由真核生物宿主包括其叶绿体的DNA组成的DNA, 线粒体, 或者只在宿主体内繁殖的质粒.

rDNA consisting entirely of DNA segments from different species that exchange DNA by known physiological processes.

The rDNA activities listed above are exempt from full review before labwork is initiated; however, 生物项目登记表必须提交给IBC.

涉及生物材料、活生物体和动物的活动:

Biosafety Level 1 (BSL1) materials are not known to cause disease in healthy adults are exempt from full review. 生物项目登记表必须提交给IBC.

液体, 组织, 源自人类或非人类灵长类动物的细胞和其他生物材料被归类为BSL2. 涉及BSL2材料的项目有 不能幸免 from full IBC review and are not authorized until the protocols are reviewed and approved by the IBC.

使用以下内容 选择代理 研究人员在获得材料之前必须经过IBC的批准.

红豆因, 个与, Diacetoxyscirpenol (DAS), 蓖麻毒蛋白, 蛤蚌毒素, 河豚毒素, 志贺样核糖体灭活蛋白, 肉毒神经毒素, 产气荚膜梭菌毒素, Shigatoxin, 葡萄球菌肠毒素, 2毒素

调查员资源

教师培训是强制性的, 工作人员, 学生从事涉及重组DNA和/或非固定生物材料的活动.

生物安全课程

培训是通过合作机构培训计划(CITI)进行的。.

培训说明:

  • 打开web浏览器并继续执行 www.citiprogram.org
     
  • 点击“新用户在此注册”链接创建一个新帐户.
    • 第一节. Select your institution or organization: choose “Rhode Island College” from the Participating Institutions pull-down list. 将其他下拉列表留空.
    • 第二节. Select your Username and Password: choose a username and password that you will remember and note them for your records. 
    • 第三节.  输入你的名字:输入你的姓和名.
    • 第四节. 输入您的电子邮件地址:列出首选的电子邮件地址.
    • 单击页面底部的Submit按钮继续.
       
  • 下一页打开了一个名为, “请提供esball官方网要求的以下信息.”
     
  • 用红色星号完成标记为强制性的每一行. 单击页面底部的Submit按钮继续.
     
  • 下一页的标题是，“选择课程-esball官方网”. 在这里，你为每个人注册一门课程 学习者群体 提供培训的地方. 一旦你的帐户被创建，你可以注册任何你想要或需要的课程. There is no need to pick one course in each content area unless you have been specifically requested to do so. 单击页面底部的Submit按钮继续.
     
  • 下一页写道:“此时，您可以在另一个机构注册.“你可以在未来的任何时候添加从属关系. 大多数人应该点击No按钮，只与esball官方网保持联系.
     
  • 您的帐户创建完成. 你现在可以参加和注册课程, 改变学习者群体和隶属关系, 并进行其他账户维护.
     
  • 一旦您完成了课程，RIC赞助项目办公室将收到确认. ​

The 院校生物安全委员会 (IBC) has been established as specified in the NIH Guidelines for Research Involving Recombinant DNA Molecules and CDC Guidelines for Biosafety in Microbiological and Biomedical Laboratories. RIC IBC监督涉及重组DNA的研究, 制定政策并提供专业知识以减少教师面临的风险, 从事生物有害材料和重组DNA技术工作的教职员工和学生.  RIC IBC reviews 研究 protocols to determine whether a Principal Investigator (PI) who administers, 处理或使用生物材料采用密封, 去污, 处置程序也要符合联邦, 州和地方法规, 并确保用户在良好的微生物技术方面得到适当的培训.

IBC组成, 标准, and procedures follow the NIH Guidelines For Research Involving recombinant DNA molecules Sections I-E-2 through IV-B-2-b-(9)). The RIC IBC is comprised of six members with expertise in recombinant DNA technology and the capability to assess any potential risk of 研究 activities to public health or the environment; four members are RIC faculty and two members are not affiliated with RIC, 按照美国国立卫生研究院指南的规定.

RIC IBC在IBC网站(www)上提供资源、表格和模板.里克.edu/biosafety). Researchers can access this site to register their 研究 involving recombinant DNA molecules and cell/tissue culture experiments. 一旦收到, IBC审查研究注册表格，以确保程序到位，以保护教师, 工作人员, 还有来自生物材料的学生. 

职责:

  • 制定适用于esball官方网活动的生物安全政策, 包括工作实践, biohazardous浪费, 以及人员的医疗监控.
  • 根据CDC/NIH的指导方针审查和批准拟议的研究.
  • 为研究项目设置所需的密封级别. 一般, the biosafety levels (BSLs) established by the CDC and NIH will be used as the level of containment; however, the IBC can increase or decrease the level of containment according to the specific circumstances of the project.
  • Working with the Campus Police and the Facilities Department to recommend and review design specifications and criteria for existing and new containment facilities.
  • Evaluate the public health and environmental risks associated with all biohazardous treatment and disposal methods, including disposal of these wastes according to provisions of the Rules and Regulations for Use of Wastewater Facilities Within the Narragansett Bay Commission Dist里克t and Rhode Island Regulation DEM-DAH-MW-01-92.
  • 必要时, 对有害生物废物管理程序的管理和变更提出建议. ​